We develop and validate methods for organizing, summarizing and visualizing complex biological data for systems biology through the integration of bioinformatics and biostatistics.
Measurements are performed on a complex system probing parts A, B, and C of that system. The resulting data blocks X1, X2, and X3 contain mixed variation, which has to be separated in sources (red/green is common; yellow is distinct; grey is irrelevant variation and noise). These quantified sources are then used to reconstruct the system. This paper concerns mainly the box within the blue lines.
The paper entitled Covariances Simultaneous Component Analysis: a new method within a framework for modeling covariances, authored by Age K. Smilde, Marieke E. Timmerman, Edoardo Saccenti, Jeroen J. Jansen and Huub C. J. Hoefsloot has been selected as the winner of the 2017 Kowalski prize for the "Best Application Paper" published in the Journal of Chemometrics in 2015 and 2016. The selection committee read more
Age Smilde, Robert Hall (Wageningen Universiteit & Researchcentrum) and Thomas Hankemeier (Universiteit Leiden) have been awarded a NWO Technology Area (TA)-grant to study, together with food companies DSM and Unilever, the flavour profile of food products read more
The award winning paper by Ewa Szymańska and her collegues from the BDA group received extra attention when it featured on the front page of the October issue of Metabolomics.